Amy Moody

Company: Avidity Biosciences

Job title: Principle Scientist

Seminars:

Predicting & Inferring Target Coverage to Optimize Human Dose Selection 3:30 pm

Utilizing preclinical data to build sophisticated computational models relating exposure, knock-down, and biomarkers Improving interspecies translation and human dose prediction by using mechanistic approach to model development Maximizing understanding of target coverage throughout dosing interval from limited clinical dataRead more

day: Day Two

Roundtable Discussion: Unleashing the Potential of Computational Models for Predicting Clearance, Toxicity & Dosing to Accelerate Therapeutic Translation into the Clinic 4:00 pm

How to leverage AI/ML to gain better predictive power of human exposure and clearance from high throughput in vitro assays Shorten RNA design cycles by utilizing clinical and toxicology datasets to better understand translation and improve in vivo prediction How to fast-track from RNA discovery to the clinic by integrating AI/ML into preclinical strategies?Read more

day: Day Two