Sizhen Li

Company: Sanofi

Job title: Computational Scientist Lead

Seminars:

Leveraging a Small Language Model to Achieve Full-Length mRNA Analysis with Improved Prediction of Stability & Translation Efficiency 12:25 pm

CodonBERT is pre-trained on 10 million mRNA sequences to capture codon dependencies and interactions across different species mRNA-LM extends CodonBERT from the CDS to full-length mRNA by integrating two pre-trained BERT models on UTR regions Both CodonBERT and mRNA-LM show significant improvements in predicting mRNA properties compared to existing methodsRead more

day: Day One

Panel Discussion: Driving Safer Delivery of RNA Therapeutics & Vaccines by Leveraging Computational Tools with Better Prediction of Targeting & Specificity 12:00 pm

What makes antibody/ligand engineering different between general applications vs RNA-specific ones? How does engineering address processes after binding a target cell? Uncovering which factors to consider when deciding the tool to be used for a specific problemRead more

day: Day Two